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Systemic candidiasis: A condition which only affects people with compromised immune systems, for example, those who are HIV-positive, have cancer or are on immune suppressive drugs after organ transplantation.

Candida fungi contaminate the bloodstream and spread throughout the body, causing severe infection.

If the doctor suspects cutaneous candidiasis, questions will be asked about skin care and about conditions that could expose the skin to excessive moisture, such as wearing overly tight clothing or rubber gloves.

Thrush, cutaneous candidiasis or vaginal yeast infection can often be diagnosed by a simple physical examination and viewing a scraping sample through a microscope at the doctor's office.

The infection commonly occurs as a result of self contamination with yeast organisms from the rectal passage. Vaginal candida infections are not usually transmitted sexually.